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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA1
All Species:
27.58
Human Site:
Y243
Identified Species:
50.56
UniProt:
Q13131
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13131
NP_006242.5
559
64009
Y243
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086285
574
65620
Y258
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Dog
Lupus familis
XP_536491
563
64691
Y247
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5EG47
559
63911
Y243
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Rat
Rattus norvegicus
P54645
559
63955
Y243
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
S214
Y
L
N
P
S
V
I
S
L
L
K
H
M
L
Q
Chicken
Gallus gallus
Q9IA88
798
88848
R241
R
V
L
E
G
R
F
R
I
P
Y
F
M
S
E
Frog
Xenopus laevis
NP_001083882
560
64031
Y243
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Zebra Danio
Brachydanio rerio
NP_001103756
573
65002
F233
K
I
C
D
G
I
F
F
T
P
Q
Y
L
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
D218
L
C
G
T
L
P
F
D
D
E
H
V
P
T
L
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
P303
K
I
K
S
G
V
F
P
T
P
D
F
L
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
L233
C
G
V
I
L
Y
A
L
L
C
G
T
L
P
F
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
T270
N
I
S
N
G
V
Y
T
L
P
K
F
L
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
92.5
N.A.
98.7
99.1
N.A.
89.2
27
88.7
84.4
N.A.
N.A.
62.2
53.5
N.A.
Protein Similarity:
100
N.A.
97.3
93.7
N.A.
99.4
99.6
N.A.
91
43.1
94.6
90.9
N.A.
N.A.
75.1
66.4
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
20
100
93.3
N.A.
N.A.
6.6
46.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
60
100
100
N.A.
N.A.
6.6
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45
33.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.4
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
8
8
54
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
54
0
0
0
8
8
0
8
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
77
8
0
0
0
24
0
0
8
% F
% Gly:
0
8
8
0
77
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
70
0
8
0
54
8
0
8
0
0
0
0
0
0
% I
% Lys:
62
0
8
0
0
0
0
0
0
0
16
0
0
0
0
% K
% Leu:
8
8
8
0
16
0
0
8
24
8
0
0
77
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
8
0
8
8
0
0
0
0
0
0
0
0
0
54
0
% N
% Pro:
0
0
0
8
0
8
0
8
0
77
0
0
8
8
62
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
8
% Q
% Arg:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% R
% Ser:
0
0
8
8
8
0
0
8
0
0
0
0
0
16
0
% S
% Thr:
0
0
0
8
0
0
0
8
62
0
0
8
0
8
0
% T
% Val:
0
8
8
0
0
24
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
8
47
0
0
8
54
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _